Basic Information
ID: ALA4155124
Type: Binding
Description: Inhibition of Escherichia coli C-terminal His6-tagged DNA gyrase B expressed in Escherichia coli BL21(DE3) assessed as residual activity at 1 uM preincubated for 10 mins followed by ATP addition measured after 30 mins by purine nucleoside phosphorylase enzyme coupled spectrophotometric method relative to control
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4155124
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 612.63 | 3.63 | 3.63 |
| 428.27 | 3.48 | 3.48 |
| 517.17 | 3.78 | 3.78 |
| 536.22 | 4.90 | 4.90 |
| 456.33 | 3.96 | 3.96 |
| 607.30 | 5.09 | 5.09 |
| 545.23 | 4.42 | 4.42 |
| 493.78 | 2.51 | 2.51 |
| 479.75 | 2.42 | 2.42 |
| 442.30 | 3.57 | 3.57 |
| 442.30 | 3.87 | 3.87 |
| 483.31 | 2.39 | 2.39 |
| 618.28 | 3.60 | 3.60 |
| 532.42 | 5.18 | 5.18 |
| 543.40 | 3.99 | 3.99 |
| 565.22 | 4.27 | 4.27 |
| 540.60 | 1.94 | 1.94 |
| 551.19 | 4.19 | 4.19 |
| 482.32 | 3.84 | 3.84 |
| 557.43 | 4.08 | 4.08 |
| 604.25 | 3.51 | 3.51 |
| 522.20 | 5.23 | 5.23 |
| 456.33 | 3.96 | 3.96 |
| 559.26 | 4.51 | 4.51 |
| 644.75 | 3.64 | 3.64 |
| 517.17 | 3.48 | 3.48 |
| 503.15 | 3.39 | 3.39 |
| 593.27 | 5.00 | 5.00 |
| 583.43 | 3.95 | 3.95 |
| 708.40 | 5.21 | 5.21 |
| 531.20 | 3.87 | 3.87 |
| 694.38 | 5.12 | 5.12 |
| 456.33 | 2.78 | 2.78 |
| 504.14 | 1.94 | 1.94 |
| 557.44 | 2.89 | 2.89 |
| 546.22 | 2.64 | 2.64 |
| 442.30 | 3.87 | 3.87 |
| 630.72 | 3.56 | 3.56 |
| 518.40 | 5.10 | 5.10 |