Basic Information
ID: ALA4155128
Type: Binding
Description: Inhibition of Escherichia coli C-terminal His6-tagged topoisomerase-4 expressed in Escherichia coli BL21(DE3) assessed as residual activity at 1 uM preincubated for 10 mins followed by ATP addition measured after 30 mins by purine nucleoside phosphorylase enzyme coupled spectrophotometric method relative to control
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4155128
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 517.17 | 3.78 | 3.78 |
| 493.78 | 2.51 | 2.51 |
| 543.40 | 3.99 | 3.99 |
| 551.19 | 4.19 | 4.19 |
| 503.15 | 3.39 | 3.39 |
| 456.33 | 2.78 | 2.78 |
| 630.72 | 3.56 | 3.56 |