Assay Report Card

Basic Information

ID: ALA4155129

Type: Binding

Description: Inhibition of Staphylococcus aureus topoisomerase-4 assessed as residual activity at 1 uM preincubated for 10 mins followed by ATP addition measured after 30 mins by purine nucleoside phosphorylase enzyme coupled spectrophotometric method relative to control

Organism: Staphylococcus aureus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
517.173.783.78
543.403.993.99
503.153.393.39
456.332.782.78
630.723.563.56