Basic Information
ID: ALA4155485
Type: Binding
Description: Inhibition of Ca2+/calmodulin-induced full-length recombinant human N-terminal GST-tagged PDE1C expressed in baculovirus infected Sf9 insect cells using cAMP as substrate pretreated for 10 mins followed by substrate addition and measured after 30 mins by kinase-Glo luminescence assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4155485
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.27 | 3.88 | 3.88 |
| 347.41 | 3.41 | 3.41 |
| 346.42 | 4.01 | 4.01 |
| 371.40 | 3.36 | 3.36 |
| 330.35 | 3.54 | 3.54 |
| 375.82 | 3.77 | 3.77 |
| 359.37 | 3.26 | 3.26 |
| 419.29 | 4.71 | 4.71 |
| 370.42 | 3.96 | 3.96 |
| 361.43 | 3.72 | 3.72 |
| 341.38 | 3.35 | 3.35 |
| 340.39 | 3.95 | 3.95 |
| 371.40 | 3.13 | 3.13 |
| 361.43 | 3.72 | 3.72 |
| 358.38 | 4.09 | 4.09 |
| 341.38 | 3.12 | 3.12 |
| 359.37 | 3.49 | 3.49 |
| 347.41 | 3.41 | 3.41 |
| 340.39 | 3.95 | 3.95 |
| 341.38 | 3.12 | 3.12 |
| 358.38 | 4.09 | 4.09 |
| 348.40 | 2.57 | 2.57 |
| 380.86 | 4.67 | 4.67 |
| 342.37 | 2.51 | 2.51 |
| 341.38 | 3.35 | 3.35 |