Basic Information
ID: ALA4155951
Type: Functional
Description: Antagonist activity at recombinant human GPR55 expressed in CHO cells assessed as inhibition of lysophosphatidylinositol-induced beta-arrestin recruitment preincubated for 60 mins followed by lysophosphatidylinositol addition for 90 mins measured for 1 sec by luminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: G-protein coupled receptor 55(ALA1075322)
Document: ALA4152303
Antagonist activity at recombinant human GPR55 expressed in CHO cells assessed as inhibition of lysophosphatidylinositol-induced beta-arrestin recruitment preincubated for 60 mins followed by lysophosphatidylinositol addition for 90 mins measured for 1 sec by luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4155951
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 452.94 | 5.82 | 5.82 |
| 485.05 | 6.42 | 6.42 |
| 345.81 | 4.24 | 4.24 |
| 344.82 | 3.26 | 3.26 |
| 368.43 | 4.08 | 4.08 |
| 464.63 | 6.00 | 6.00 |
| 428.94 | 4.86 | 4.86 |
| 414.91 | 4.47 | 4.47 |
| 513.84 | 6.44 | 6.44 |
| 471.02 | 6.03 | 6.03 |
| 358.85 | 4.11 | 4.11 |
| 464.63 | 5.94 | 5.94 |
| 364.47 | 3.98 | 3.98 |
| 463.00 | 6.33 | 6.33 |
| 434.95 | 5.68 | 5.68 |
| 429.34 | 4.70 | 4.70 |
| 471.02 | 6.03 | 6.03 |
| 370.86 | 4.20 | 4.20 |
| 378.50 | 4.37 | 4.37 |
| 499.08 | 6.81 | 6.81 |
| 341.80 | 3.26 | 3.26 |
| 469.39 | 6.33 | 6.33 |
| 471.02 | 6.03 | 6.03 |
| 478.66 | 6.50 | 6.50 |
| 442.97 | 5.25 | 5.25 |
| 364.47 | 4.25 | 4.25 |
| 361.88 | 4.41 | 4.41 |
| 448.98 | 5.99 | 5.99 |
| 372.88 | 4.45 | 4.45 |
| 450.60 | 5.69 | 5.69 |
| 457.00 | 5.64 | 5.64 |
| 370.86 | 4.20 | 4.20 |
| 448.98 | 5.72 | 5.72 |