Basic Information
ID: ALA4156262
Type: Binding
Description: Inhibition of recombinant His-tagged SIRT2 (56 to 356 residues) (unknown origin) expressed in Escherichia coli Transetta(DE3) using AcIQF as substrate preincubated for 30 mins followed by substrate and NAD+ addition measured after 2 hrs by fluorescence assay
Format: BAO_0000019
Organism: Homo sapiens
Target: NAD-dependent deacetylase sirtuin 2(ALA4462)
Document: ALA4152324
Inhibition of recombinant His-tagged SIRT2 (56 to 356 residues) (unknown origin) expressed in Escherichia coli Transetta(DE3) using AcIQF as substrate preincubated for 30 mins followed by substrate and NAD+ addition measured after 2 hrs by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4156262
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.56 | 5.02 | 5.02 |
| 504.64 | 5.72 | 5.72 |
| 379.49 | 4.40 | 4.40 |
| 502.60 | 4.39 | 4.39 |
| 494.62 | 5.75 | 5.75 |
| 504.63 | 6.32 | 6.32 |
| 465.56 | 4.43 | 4.43 |
| 506.63 | 4.77 | 4.77 |
| 479.61 | 4.08 | 4.08 |
| 488.57 | 5.25 | 5.25 |
| 493.59 | 3.48 | 3.48 |
| 499.60 | 5.05 | 5.05 |
| 513.58 | 4.02 | 4.02 |
| 491.62 | 4.09 | 4.09 |
| 507.64 | 5.48 | 5.48 |
| 579.72 | 5.65 | 5.65 |
| 508.60 | 6.75 | 6.75 |
| 563.72 | 4.62 | 4.62 |
| 504.64 | 5.72 | 5.72 |
| 591.73 | 5.74 | 5.74 |
| 515.62 | 5.35 | 5.35 |
| 585.69 | 5.27 | 5.27 |
| 538.70 | 3.83 | 3.83 |
| 488.57 | 5.25 | 5.25 |
| 462.58 | 4.92 | 4.92 |
| 502.60 | 4.39 | 4.39 |
| 480.59 | 4.38 | 4.38 |
| 488.63 | 6.62 | 6.62 |
| 491.62 | 4.09 | 4.09 |
| 506.63 | 4.77 | 4.77 |
| 507.64 | 5.48 | 5.48 |
| 465.58 | 3.69 | 3.69 |
| 577.75 | 5.02 | 5.02 |
| 499.60 | 5.05 | 5.05 |
| 486.59 | 6.21 | 6.21 |
| 506.56 | 5.42 | 5.42 |
| 591.73 | 5.74 | 5.74 |
| 480.58 | 3.83 | 3.83 |
| 565.70 | 5.26 | 5.26 |
| 552.73 | 4.22 | 4.22 |