Basic Information
ID: ALA4156266
Type: Binding
Description: Inhibition of recombinant human N-terminal His6-tagged SIRT6 (4 to 296 residues) expressed in Escherichia coli Transetta(DE3) using AcIQF as substrate preincubated for 30 mins followed by substrate and NAD+ addition measured after 2 hrs by fluorescence assay
Format: BAO_0000019
Organism: Homo sapiens
Target: NAD-dependent protein deacetylase sirtuin-6(ALA2163182)
Document: ALA4152324
Inhibition of recombinant human N-terminal His6-tagged SIRT6 (4 to 296 residues) expressed in Escherichia coli Transetta(DE3) using AcIQF as substrate preincubated for 30 mins followed by substrate and NAD+ addition measured after 2 hrs by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4156266
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 502.60 | 4.39 | 4.39 |