Basic Information
ID: ALA4156287
Type: Binding
Description: Inhibition of L-type voltage gated calcium channel in human SH-SY5Y cells assessed as blockade of K+-evoked calcium uptake at 1 uM pretreated for 10 mins followed by KCl/CaCl2 addition and measured for 55 secs by Fluo-4AM dye based fluorescence assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: SH-SY5Y
Target: Voltage-gated L-type calcium channel(ALA2095229)
Document: ALA4152325
Inhibition of L-type voltage gated calcium channel in human SH-SY5Y cells assessed as blockade of K+-evoked calcium uptake at 1 uM pretreated for 10 mins followed by KCl/CaCl2 addition and measured for 55 secs by Fluo-4AM dye based fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4156287
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 198.27 | 2.70 | 2.70 |
| 418.45 | 2.97 | 2.97 |
| 328.42 | 3.07 | 3.07 |
| 340.45 | 2.94 | 2.94 |
| 324.45 | 3.24 | 3.24 |
| 355.42 | 2.84 | 2.84 |
| 324.45 | 3.24 | 3.24 |
| 344.87 | 3.59 | 3.59 |
| 354.44 | 2.66 | 2.66 |
| 310.43 | 2.93 | 2.93 |
| 340.45 | 2.94 | 2.94 |
| 389.32 | 3.69 | 3.69 |
| 353.50 | 3.00 | 3.00 |
| 340.45 | 2.94 | 2.94 |