Basic Information
ID: ALA4156811
Type: Functional
Description: Antagonist activity at CXCR4 in human CCRF-CEM cells assessed as inhibition of SDF-1alpha-induced calcium release preincubated for 25 mins followed by SDF-1alpha stimulation and measured for 90 secs by calcium flux assay
Organism: Homo sapiens
Cell type: CCRF-CEM
Activity Charts
Bioactivity
Activity Types for Assay ALA4156811
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.54 | 3.21 | 3.21 |
| 482.68 | 3.82 | 3.82 |
| 419.62 | 3.29 | 3.29 |
| 379.55 | 2.25 | 2.25 |
| 535.66 | 5.45 | 5.45 |
| 391.56 | 2.51 | 2.51 |
| 431.63 | 3.39 | 3.39 |
| 403.57 | 2.66 | 2.66 |
| 419.62 | 3.25 | 3.25 |
| 419.62 | 3.29 | 3.29 |
| 431.63 | 3.30 | 3.30 |
| 405.59 | 2.86 | 2.86 |
| 365.53 | 1.95 | 1.95 |
| 469.64 | 3.22 | 3.22 |
| 431.63 | 3.39 | 3.39 |
| 405.59 | 2.86 | 2.86 |
| 509.69 | 4.71 | 4.71 |
| 405.59 | 2.91 | 2.91 |
| 365.53 | 1.95 | 1.95 |
| 468.65 | 3.83 | 3.83 |
| 433.64 | 3.63 | 3.63 |
| 431.63 | 3.25 | 3.25 |
| 433.64 | 3.64 | 3.64 |
| 391.56 | 2.51 | 2.51 |
| 421.59 | 1.88 | 1.88 |
| 419.62 | 3.29 | 3.29 |
| 431.63 | 3.39 | 3.39 |
| 447.63 | 2.63 | 2.63 |
| 403.57 | 2.66 | 2.66 |
| 473.71 | 4.47 | 4.47 |
| 435.62 | 2.53 | 2.53 |
| 405.59 | 2.82 | 2.82 |
| 419.62 | 3.30 | 3.30 |
| 419.62 | 3.20 | 3.20 |