Basic Information
ID: ALA4156813
Type: ADME
Description: Inhibition of recombinant human CYP2D6 expressed in insect cells microsomes using AMMC as substrate preincubated for 30 mins followed by NADP addition and measured after 45 mins by fluorescence analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4156813
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.54 | 3.21 | 3.21 |
| 482.68 | 3.82 | 3.82 |
| 419.62 | 3.29 | 3.29 |
| 379.55 | 2.25 | 2.25 |
| 535.66 | 5.45 | 5.45 |
| 391.56 | 2.51 | 2.51 |
| 431.63 | 3.39 | 3.39 |
| 403.57 | 2.66 | 2.66 |
| 419.62 | 3.25 | 3.25 |
| 419.62 | 3.29 | 3.29 |
| 431.63 | 3.30 | 3.30 |
| 405.59 | 2.86 | 2.86 |
| 365.53 | 1.95 | 1.95 |
| 469.64 | 3.22 | 3.22 |
| 431.63 | 3.39 | 3.39 |
| 405.59 | 2.86 | 2.86 |
| 509.69 | 4.71 | 4.71 |
| 405.59 | 2.91 | 2.91 |
| 365.53 | 1.95 | 1.95 |
| 468.65 | 3.83 | 3.83 |
| 433.64 | 3.63 | 3.63 |
| 431.63 | 3.25 | 3.25 |
| 433.64 | 3.64 | 3.64 |
| 391.56 | 2.51 | 2.51 |
| 421.59 | 1.88 | 1.88 |
| 419.62 | 3.29 | 3.29 |
| 431.63 | 3.39 | 3.39 |
| 447.63 | 2.63 | 2.63 |
| 403.57 | 2.66 | 2.66 |
| 473.71 | 4.47 | 4.47 |
| 435.62 | 2.53 | 2.53 |
| 405.59 | 2.82 | 2.82 |
| 419.62 | 3.30 | 3.30 |
| 419.62 | 3.20 | 3.20 |