Basic Information
ID: ALA4156823
Type: Binding
Description: Inhibition of GST-tagged full length recombinant human VPS34 expressed in Baculovirus expression system using PI:PS as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr in presence of 50 uM ATP by ADP-Glo luminescence assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Phosphatidylinositol 3-kinase catalytic subunit type 3(ALA1075165)
Document: ALA4152344
Inhibition of GST-tagged full length recombinant human VPS34 expressed in Baculovirus expression system using PI:PS as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr in presence of 50 uM ATP by ADP-Glo luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4156823
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 513.65 | 2.15 | 2.15 |
| 415.43 | 3.75 | 3.75 |
| 494.04 | 4.20 | 4.20 |
| 494.04 | 4.20 | 4.20 |
| 494.04 | 4.20 | 4.20 |