Basic Information
ID: ALA4156826
Type: Binding
Description: Inhibition of PI3Kgamma (unknown origin) using PIP2:PS as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr in presence of 50 uM ATP by ADP-Glo luminescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: PI3-kinase p110-gamma subunit(ALA3267)
Document: ALA4152344
Inhibition of PI3Kgamma (unknown origin) using PIP2:PS as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr in presence of 50 uM ATP by ADP-Glo luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4156826
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 513.65 | 2.15 | 2.15 |
| 415.43 | 3.75 | 3.75 |
| 494.04 | 4.28 | 4.28 |
| 494.04 | 4.28 | 4.28 |
| 467.96 | 2.23 | 2.23 |
| 514.46 | 4.54 | 4.54 |
| 480.02 | 3.89 | 3.89 |
| 417.52 | 2.60 | 2.60 |
| 494.04 | 4.20 | 4.20 |
| 419.49 | 1.92 | 1.92 |
| 433.52 | 2.22 | 2.22 |
| 548.01 | 4.91 | 4.91 |
| 548.91 | 5.20 | 5.20 |
| 494.04 | 4.20 | 4.20 |
| 463.97 | 3.40 | 3.40 |
| 548.91 | 5.20 | 5.20 |
| 436.95 | 4.32 | 4.32 |
| 536.12 | 5.19 | 5.19 |
| 548.91 | 5.20 | 5.20 |
| 481.99 | 2.61 | 2.61 |
| 465.99 | 3.64 | 3.64 |
| 514.46 | 4.54 | 4.54 |
| 417.52 | 2.60 | 2.60 |
| 436.95 | 3.47 | 3.47 |
| 516.00 | 4.17 | 4.17 |
| 528.06 | 4.48 | 4.48 |
| 478.00 | 3.64 | 3.64 |
| 437.93 | 2.86 | 2.86 |
| 480.02 | 3.89 | 3.89 |
| 417.52 | 2.52 | 2.52 |
| 522.10 | 5.01 | 5.01 |
| 422.92 | 3.93 | 3.93 |
| 494.04 | 4.20 | 4.20 |
| 465.99 | 3.64 | 3.64 |
| 548.91 | 5.20 | 5.20 |
| 514.46 | 4.54 | 4.54 |
| 465.99 | 3.64 | 3.64 |
| 556.11 | 5.56 | 5.56 |
| 403.49 | 2.21 | 2.21 |