Basic Information
ID: ALA4156840
Type: Binding
Description: Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as C5a-induced reduction in phosphorylation of AKT at Ser473 residues preincubated for 1 hr followed by C5a stimulation and measured after 5 mins by PAGE analysis
Format: BAO_0000219
Organism: Mus musculus
Cell type: RAW264.7
Target: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(ALA2189158)
Document: ALA4152344
Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as C5a-induced reduction in phosphorylation of AKT at Ser473 residues preincubated for 1 hr followed by C5a stimulation and measured after 5 mins by PAGE analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4156840
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 494.04 | 4.20 | 4.20 |