Basic Information
ID: ALA4156841
Type: Binding
Description: Inhibition of PI3Kdelta in human Raji cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Thr308 residues preincubated for 1 hr followed by anti-IgM antibody stimulation and measured after 5 mins by PAGE analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Raji
Target: PI3-kinase p110-delta subunit(ALA3130)
Document: ALA4152344
Inhibition of PI3Kdelta in human Raji cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Thr308 residues preincubated for 1 hr followed by anti-IgM antibody stimulation and measured after 5 mins by PAGE analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4156841
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 494.04 | 4.20 | 4.20 |