Basic Information
ID: ALA4157344
Type: Binding
Description: Inhibition of F1F0-ATP synthase subunit C in human HeLa cells assessed as reduction of ionomycin-induced Ca2+ mediated mPTP opening at 1 uM preincubated for 30 secs followed by ionomycin addition by calcein-cobalt based assay relative to control
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA4157344
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 321.42 | 2.62 | 2.62 |
| 363.51 | 3.74 | 3.74 |
| 361.49 | 4.22 | 4.22 |
| 389.45 | 1.94 | 1.94 |
| 337.40 | 3.24 | 3.24 |
| 356.47 | 2.46 | 2.46 |
| 389.42 | 3.63 | 3.63 |
| 387.40 | 4.12 | 4.12 |
| 385.49 | 2.11 | 2.11 |
| 335.41 | 2.26 | 2.26 |
| 339.41 | 2.75 | 2.75 |
| 353.85 | 3.75 | 3.75 |
| 429.93 | 2.66 | 2.66 |
| 349.43 | 3.10 | 3.10 |
| 319.41 | 3.10 | 3.10 |
| 350.42 | 2.65 | 2.65 |
| 335.45 | 2.92 | 2.92 |
| 411.94 | 2.52 | 2.52 |
| 273.34 | 0.96 | 0.96 |
| 351.45 | 2.62 | 2.62 |
| 309.39 | 0.37 | 0.37 |
| 355.87 | 3.27 | 3.27 |
| 407.44 | 2.08 | 2.08 |
| 372.54 | 2.62 | 2.62 |
| 333.44 | 3.40 | 3.40 |