Basic Information
ID: ALA4157375
Type: Binding
Description: Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured MDH refolding by measuring MDH enzyme activity using sodium mesoxalate as substrate after 20 to 40 mins by spectrometric analysis
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4157375
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 595.57 | 4.91 | 4.91 |
| 641.57 | 7.13 | 7.13 |
| 574.47 | 6.40 | 6.40 |
| 614.05 | 6.83 | 6.83 |
| 648.49 | 7.48 | 7.48 |
| 625.49 | 6.37 | 6.37 |
| 586.53 | 6.53 | 6.53 |
| 614.94 | 7.12 | 7.12 |
| 625.49 | 6.37 | 6.37 |
| 588.05 | 5.35 | 5.35 |
| 575.09 | 5.27 | 5.27 |
| 648.49 | 7.48 | 7.48 |
| 575.09 | 5.27 | 5.27 |
| 614.05 | 6.83 | 6.83 |