Basic Information
ID: ALA4157376
Type: Binding
Description: Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured rhodanese refolding by measuring rhodanese enzyme activity after 45 mins by spectrometric analysis
Format: BAO_0000019
Organism: Escherichia coli
Target: GroEL/GroES(ALA4106139)
Document: ALA4152346
Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured rhodanese refolding by measuring rhodanese enzyme activity after 45 mins by spectrometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4157376
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 595.57 | 4.91 | 4.91 |
| 641.57 | 7.13 | 7.13 |
| 574.47 | 6.40 | 6.40 |
| 614.05 | 6.83 | 6.83 |
| 648.49 | 7.48 | 7.48 |
| 625.49 | 6.37 | 6.37 |
| 586.53 | 6.53 | 6.53 |
| 614.94 | 7.12 | 7.12 |
| 625.49 | 6.37 | 6.37 |
| 588.05 | 5.35 | 5.35 |
| 575.09 | 5.27 | 5.27 |
| 648.49 | 7.48 | 7.48 |
| 575.09 | 5.27 | 5.27 |
| 614.05 | 6.83 | 6.83 |