Basic Information
ID: ALA4157512
Type: Binding
Description: Inhibition of Cy5-labeled cyclosporin A binding to full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) after 30 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4157512
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1090.41 | ||
| 1202.63 | ||
| 512.65 | 3.02 | 3.02 |
| 523.63 | 2.32 | 2.32 |
| 607.71 | 2.04 | 2.04 |
| 549.67 | 3.03 | 3.03 |
| 605.74 | 2.93 | 2.93 |
| 563.70 | 3.57 | 3.57 |
| 520.63 | 3.00 | 3.00 |
| 591.71 | 2.80 | 2.80 |
| 549.67 | 3.03 | 3.03 |
| 535.65 | 2.79 | 2.79 |
| 556.70 | 2.89 | 2.89 |
| 521.62 | 2.40 | 2.40 |
| 549.67 | 3.03 | 3.03 |
| 581.67 | 0.98 | 0.98 |
| 549.67 | 3.18 | 3.18 |
| 619.76 | 3.58 | 3.58 |
| 549.67 | 3.03 | 3.03 |
| 579.70 | 2.66 | 2.66 |
| 521.62 | 2.40 | 2.40 |
| 639.78 | 2.20 | 2.20 |
| 593.68 | 2.00 | 2.00 |