Basic Information
ID: ALA4157848
Type: Binding
Description: Inhibition of LfrA in Mycobacterium smegmatis MC2 155 ATCC 700084 assessed as decrease in norfloxacin MIC at 25 ug/ml after 72 hrs by MTT assay relative to control
Format: BAO_0000357
Organism: Mycolicibacterium smegmatis MC2 155
Strain: ATCC 700084
Target: Multidrug efflux pump LfrA(ALA4295530)
Document: ALA4152357
Inhibition of LfrA in Mycobacterium smegmatis MC2 155 ATCC 700084 assessed as decrease in norfloxacin MIC at 25 ug/ml after 72 hrs by MTT assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4157848
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 196.21 | 1.85 | 1.85 |
| 244.68 | 2.81 | 2.81 |
| 289.13 | 2.92 | 2.92 |
| 289.13 | 2.92 | 2.92 |
| 289.13 | 2.92 | 2.92 |
| 244.68 | 2.81 | 2.81 |
| 230.65 | 2.50 | 2.50 |
| 280.71 | 3.65 | 3.65 |