Basic Information
ID: ALA4158230
Type: Binding
Description: Inhibition of recombinant human full length MMP13 expressed in mouse NS0 cells assessed as reduction in enzyme-mediated type-2 collagen cleavage at 20 uM after 22 hrs by SDS-PAGE analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4158230
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 538.65 | 4.37 | 4.37 |
| 498.58 | 3.45 | 3.45 |
| 538.65 | 4.37 | 4.37 |
| 498.58 | 3.45 | 3.45 |
| 582.70 | 4.12 | 4.12 |
| 481.53 | 2.77 | 2.77 |
| 481.58 | 2.71 | 2.71 |
| 506.63 | 3.84 | 3.84 |
| 512.61 | 3.84 | 3.84 |
| 458.52 | 2.96 | 2.96 |
| 539.63 | 2.79 | 2.79 |
| 564.71 | 3.99 | 3.99 |
| 498.63 | 2.57 | 2.57 |
| 514.60 | 4.18 | 4.18 |
| 496.56 | 3.20 | 3.20 |
| 524.64 | 3.06 | 3.06 |
| 480.54 | 2.94 | 2.94 |
| 524.62 | 4.13 | 4.13 |
| 509.63 | 2.64 | 2.64 |
| 528.63 | 4.48 | 4.48 |
| 512.61 | 3.84 | 3.84 |
| 540.62 | 3.22 | 3.22 |
| 526.51 | 3.98 | 3.98 |
| 512.61 | 2.59 | 2.59 |
| 526.57 | 4.25 | 4.25 |
| 514.58 | 2.57 | 2.57 |
| 540.62 | 3.22 | 3.22 |
| 481.58 | 2.71 | 2.71 |
| 482.51 | 2.74 | 2.74 |
| 540.64 | 2.03 | 2.03 |
| 515.64 | 3.31 | 3.31 |
| 540.64 | 2.03 | 2.03 |