Basic Information
ID: ALA4158237
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes at 10 uM using bufuralol as substrate after 10 mins in presence of NADPH relative to control
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4158237
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 498.58 | 3.45 | 3.45 |
| 496.56 | 3.20 | 3.20 |
| 512.61 | 3.84 | 3.84 |
| 514.58 | 2.57 | 2.57 |
| 540.62 | 3.22 | 3.22 |