Basic Information
ID: ALA4158377
Type: Binding
Description: Antagonist activity at HIF-2alpha in human 786-O cells co-expressing HIF responsive element after 24 hrs by ONE-Glo luciferase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4158377
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 397.37 | 3.51 | 3.51 |
| 392.78 | 4.25 | 4.25 |
| 378.76 | 3.99 | 3.99 |
| 419.33 | 3.71 | 3.71 |
| 401.34 | 3.42 | 3.42 |
| 389.15 | 5.22 | 5.22 |
| 405.30 | 3.84 | 3.84 |
| 415.61 | 5.03 | 5.03 |
| 401.19 | 4.41 | 4.41 |
| 392.78 | 4.25 | 4.25 |
| 414.74 | 4.62 | 4.62 |
| 443.62 | 4.45 | 4.45 |
| 419.33 | 3.71 | 3.71 |
| 411.76 | 3.75 | 3.75 |
| 388.30 | 3.10 | 3.10 |
| 389.74 | 3.56 | 3.56 |
| 404.71 | 5.50 | 5.50 |
| 407.64 | 3.85 | 3.85 |
| 398.28 | 4.11 | 4.11 |
| 399.17 | 4.34 | 4.34 |
| 428.76 | 4.49 | 4.49 |
| 365.36 | 2.82 | 2.82 |
| 365.36 | 2.82 | 2.82 |
| 397.73 | 3.88 | 3.88 |
| 445.64 | 4.52 | 4.52 |
| 392.78 | 4.25 | 4.25 |
| 383.35 | 3.12 | 3.12 |
| 433.60 | 5.33 | 5.33 |
| 379.72 | 4.44 | 4.44 |
| 405.30 | 3.84 | 3.84 |
| 432.73 | 4.70 | 4.70 |
| 437.32 | 4.01 | 4.01 |