Basic Information
ID: ALA4158441
Type: Binding
Description: Antagonist activity at human TRPV4 expressed in BHK/AC9 or HEK MSR2 cells assessed as inhibition of PF-04674114-induced Ca2+ flux pre-incubated for 10 mins before agonist addition by FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4158441
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 459.33 | 3.60 | 3.60 |
| 431.27 | 2.82 | 2.82 |
| 445.30 | 3.21 | 3.21 |
| 431.27 | 2.82 | 2.82 |
| 445.30 | 3.06 | 3.06 |
| 461.30 | 2.18 | 2.18 |
| 445.30 | 3.06 | 3.06 |
| 445.30 | 3.06 | 3.06 |
| 461.30 | 2.18 | 2.18 |
| 443.33 | 4.48 | 4.48 |
| 485.42 | 1.76 | 1.76 |
| 431.27 | 2.82 | 2.82 |
| 461.30 | 2.18 | 2.18 |
| 445.30 | 3.06 | 3.06 |
| 415.27 | 3.85 | 3.85 |