Basic Information
ID: ALA4158646
Type: Functional
Description: In vivo inhibition of Nav1.7 in C57/BL6 mouse model of histamine-induced pruritis assessed as reduction in scratching bouts at 1 mg/kg, sc dosed 2 hrs before histamine challenge and measured for 15 mins relative to control
Organism: Mus musculus
Strain: C57/BL6
Activity Charts
Bioactivity
Activity Types for Assay ALA4158646
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 3686.19 | ||
| 3698.45 |