Basic Information
ID: ALA4158679
Type: Binding
Description: Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity at 10 uM preincubated for 30 mins followed by tBhQ-mediated Ca2+ depletion and Ca2+ re-addition to extracellular solution measured for 600 secs by Fluo-4 AM-based fluorometric assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4158679
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 418.27 | 4.70 | 4.70 |
| 484.44 | 3.98 | 3.98 |
| 467.33 | 4.86 | 4.86 |
| 457.41 | 3.81 | 3.81 |
| 471.40 | 4.01 | 4.01 |
| 485.42 | 4.10 | 4.10 |
| 485.42 | 4.40 | 4.40 |
| 443.34 | 3.54 | 3.54 |
| 471.40 | 4.01 | 4.01 |
| 437.38 | 3.19 | 3.19 |
| 461.83 | 4.97 | 4.97 |
| 579.58 | 6.69 | 6.69 |
| 473.41 | 4.03 | 4.03 |
| 513.48 | 5.04 | 5.04 |
| 471.40 | 4.01 | 4.01 |
| 447.37 | 4.02 | 4.02 |
| 534.45 | 4.59 | 4.59 |
| 506.47 | 2.96 | 2.96 |
| 442.36 | 2.94 | 2.94 |
| 469.42 | 4.52 | 4.52 |
| 556.50 | 3.33 | 3.33 |
| 470.41 | 3.41 | 3.41 |
| 548.50 | 3.00 | 3.00 |
| 471.40 | 4.01 | 4.01 |
| 467.33 | 4.86 | 4.86 |
| 446.36 | 3.85 | 3.85 |
| 513.48 | 5.18 | 5.18 |
| 471.40 | 4.01 | 4.01 |
| 447.37 | 4.02 | 4.02 |
| 533.47 | 5.19 | 5.19 |
| 442.40 | 3.90 | 3.90 |
| 486.41 | 3.43 | 3.43 |
| 442.40 | 3.90 | 3.90 |
| 457.37 | 3.62 | 3.62 |
| 456.64 | 4.89 | 4.89 |
| 429.36 | 3.33 | 3.33 |