Basic Information
ID: ALA4178245
Type: Binding
Description: Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins followed by antibody challenge after 18 to 24 hrs by flow cytometry
Organism: Mus musculus
Strain: C57BL/6J
Activity Charts
Bioactivity
Activity Types for Assay ALA4178245
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 589.70 | 5.16 | 5.16 |
| 602.69 | 4.83 | 4.83 |
| 615.73 | 6.17 | 6.17 |
| 629.76 | 6.05 | 6.05 |
| 614.75 | 5.45 | 5.45 |
| 614.75 | 5.45 | 5.45 |
| 632.74 | 5.59 | 5.59 |
| 601.71 | 5.53 | 5.53 |
| 595.68 | 5.55 | 5.55 |
| 596.70 | 5.64 | 5.64 |
| 648.74 | 5.68 | 5.68 |
| 587.68 | 5.39 | 5.39 |
| 580.66 | 5.27 | 5.27 |
| 646.77 | 5.98 | 5.98 |
| 600.72 | 5.45 | 5.45 |
| 637.71 | 5.05 | 5.05 |
| 591.64 | 5.31 | 5.31 |