Basic Information
ID: ALA4178339
Type: Binding
Description: Inhibition of recombinant human Cdc7 (1 to 574 residues)/human N-terminal GST-tagged DBF4 (1 to 674 residues) expressed in baculovirus expression system using His-tagged MCM2 as substrate preincubated for 10 mins followed by ATP addition by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4178339
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.33 | 3.63 | 3.63 |
| 273.36 | 3.09 | 3.09 |
| 412.49 | 3.90 | 3.90 |
| 276.37 | 2.36 | 2.36 |
| 349.46 | 4.61 | 4.61 |
| 341.23 | 2.82 | 2.82 |
| 273.36 | 3.04 | 3.04 |
| 259.33 | 2.70 | 2.70 |
| 299.40 | 3.63 | 3.63 |
| 287.39 | 3.34 | 3.34 |
| 400.55 | 4.18 | 4.18 |
| 276.37 | 2.36 | 2.36 |
| 400.55 | 4.18 | 4.18 |
| 262.34 | 2.05 | 2.05 |
| 273.36 | 2.73 | 2.73 |
| 219.27 | 1.49 | 1.49 |
| 285.37 | 3.24 | 3.24 |
| 245.26 | 1.34 | 1.34 |
| 290.39 | 2.67 | 2.67 |
| 412.49 | 3.90 | 3.90 |
| 344.36 | 3.29 | 3.29 |
| 287.39 | 3.48 | 3.48 |
| 259.33 | 2.70 | 2.70 |
| 302.40 | 3.26 | 3.26 |
| 313.43 | 4.02 | 4.02 |
| 290.39 | 2.62 | 2.62 |