Basic Information
ID: ALA4178352
Type: Binding
Description: Selectivity index, ratio of IC50 for wild-type EGFR autophosphorylation in human A549 cells to IC50 for EGFR T790M/L858R double mutant autophosphorylation in human H1975 cells
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4178352
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.46 | 1.71 | 1.71 |
| 427.49 | 2.02 | 2.02 |
| 372.79 | 4.30 | 4.30 |
| 415.43 | 0.68 | 0.68 |
| 429.46 | 1.16 | 1.16 |
| 489.63 | 3.10 | 3.10 |
| 421.51 | 1.96 | 1.96 |
| 489.63 | 2.78 | 2.78 |
| 457.51 | 1.90 | 1.90 |
| 395.47 | 1.77 | 1.77 |
| 438.58 | 2.99 | 2.99 |
| 401.41 | 0.67 | 0.67 |
| 489.63 | 3.10 | 3.10 |
| 443.49 | 1.72 | 1.72 |
| 441.52 | 2.28 | 2.28 |