Basic Information
ID: ALA4178624
Type: ADME
Description: Drug metabolism in human liver microsomes assessed as CYP3A4-mediated metabolite formation at 50 mM preincubated for 5 mins followed by NADPH addition measured after 2 hrs by UPLC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsomes
Target: Cytochrome P450 3A4(ALA340)
Document: ALA4177553
Drug metabolism in human liver microsomes assessed as CYP3A4-mediated metabolite formation at 50 mM preincubated for 5 mins followed by NADPH addition measured after 2 hrs by UPLC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4178624
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 805.78 | 1.03 | 1.03 |
| 857.81 | 1.75 | 1.75 |