Basic Information
ID: ALA4178748
Type: Functional
Description: Antiarthritic activity in Lewis rat antigen-induced arthritis model assessed as inhibition of arthritic knee swelling at 30 mg/kg, po bid for 7 days dosed after 21 and 14 days of methylated BSA and complete Freund's adjuvant sensitization measured after 7 days post dose relative to 1 mg/kg, po qd dexamethasone
Format: BAO_0000218
Organism: Rattus norvegicus
Strain: Lewis
Target: Rattus norvegicus(ALA376)
Document: ALA4177561
Antiarthritic activity in Lewis rat antigen-induced arthritis model assessed as inhibition of arthritic knee swelling at 30 mg/kg, po bid for 7 days dosed after 21 and 14 days of methylated BSA and complete Freund's adjuvant sensitization measured after 7 days post dose relative to 1 mg/kg, po qd dexamethasone: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4178748
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.53 | 4.02 | 4.02 |
| 403.53 | 2.94 | 2.94 |
| 463.63 | 2.48 | 2.48 |