Basic Information
ID: ALA4179218
Type: Binding
Description: Antiprion activity against mouse prion protein RML infected mouse ScN2a cells assessed as reduction in proteinase K-resistant PrPSc level at 10 to 100 uM incubated for 5 days followed by proteinase K digestion by Western blot method relative to control
Organism: Mus musculus
Cell type: ScN2a
Activity Charts
Bioactivity
Activity Types for Assay ALA4179218
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.39 | 4.08 | 4.08 |
| 307.35 | 3.41 | 3.41 |
| 250.32 | 2.72 | 2.72 |
| 245.28 | 2.05 | 2.05 |
| 411.44 | 4.08 | 4.08 |
| 444.51 | 4.41 | 4.41 |