Basic Information
ID: ALA4179491
Type: Binding
Description: Selectivity ratio of IC50 for human CYP3A4 expressed in Escherichia coli co-expressing CYP-reductase to IC50 for trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells
Format: BAO_0000219
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4177592
Selectivity ratio of IC50 for human CYP3A4 expressed in Escherichia coli co-expressing CYP-reductase to IC50 for trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4179491
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 513.65 | 4.36 | 4.36 |
| 539.69 | 4.74 | 4.74 |
| 527.68 | 4.62 | 4.62 |
| 570.17 | 5.52 | 5.52 |
| 557.71 | 4.24 | 4.24 |
| 544.14 | 5.13 | 5.13 |
| 543.68 | 3.59 | 3.59 |
| 556.15 | 5.26 | 5.26 |
| 529.65 | 3.33 | 3.33 |