Basic Information
ID: ALA4179998
Type: Functional
Description: Antitrypanosomal activity against Trypanosoma cruzi Y trypomastigote infected in monkey LLC-MK2 cells assessed as inhibition of cell invasion by trypanosoma by measuring infected fibroblast at 250 uM pretreated with cells for 30 mins followed by trypomastigote infection measured after 18 hrs by panoptic dye-based optical microscopic analysis (Rvb = 63%)
Organism: Trypanosoma cruzi
Strain: Y
Cell type: LLC-MK2
Activity Charts
Bioactivity
Activity Types for Assay ALA4179998
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 522.54 | -0.86 | -0.86 |
| 472.48 | -1.94 | -1.94 |
| 430.44 | -2.11 | -2.11 |
| 536.57 | -0.55 | -0.55 |
| 511.51 | -0.66 | -0.66 |
| 507.53 | -0.57 | -0.57 |
| 568.57 | -1.15 | -1.15 |