Assay Report Card

Basic Information

ID: ALA4179999

Type: Functional

Description: Antitrypanosomal activity against Trypanosoma cruzi Y trypomastigote infected in monkey LLC-MK2 cells assessed as inhibition of cell invasion by trypanosoma by measuring mean number of amastigote parasites per cells at 250 uM pretreated with cells for 30 mins followed by trypomastigote infection measured after 18 hrs by panoptic dye-based optical microscopic analysis

Organism: Trypanosoma cruzi

Strain: Y

Cell type: LLC-MK2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
522.54-0.86-0.86
472.48-1.94-1.94
430.44-2.11-2.11
536.57-0.55-0.55
511.51-0.66-0.66
507.53-0.57-0.57
568.57-1.15-1.15