Assay Report Card

Basic Information

ID: ALA4180000

Type: Functional

Description: Antitrypanosomal activity against Trypanosoma cruzi Y trypomastigote infected in monkey LLCMK2 cells assessed as inhibition of cell invasion by trypanosoma by measuring infection index at 250 uM pretreated with cells for 30 mins followed by trypomastigote infection measured after 18 hrs by panoptic dye-based optical microscopic analysis (Rvb = 68 No_unit)

Organism: Trypanosoma cruzi

Strain: Y

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
522.54-0.86-0.86
472.48-1.94-1.94
430.44-2.11-2.11
536.57-0.55-0.55
511.51-0.66-0.66
507.53-0.57-0.57
568.57-1.15-1.15