Basic Information
ID: ALA4180093
Type: ADME
Description: Reduction in intraocular pressure in Wistar rat model of dexamethasone-induced elevated IOP assessed as change in intraocular pressure in contralateral eye at 1 % w/v after 6 hrs by tonometry (Rvb = 0%)
Organism: Rattus norvegicus
Strain: Wistar
Activity Charts
Bioactivity
Activity Types for Assay ALA4180093
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.84 | 1.22 | 1.22 |
| 425.54 | 3.91 | 3.91 |
| 273.34 | 0.75 | 0.75 |
| 363.47 | 2.36 | 2.36 |
| 380.41 | 2.23 | 2.23 |
| 349.44 | 2.32 | 2.32 |
| 335.41 | 2.32 | 2.32 |
| 287.37 | 1.14 | 1.14 |
| 336.40 | 1.72 | 1.72 |
| 365.44 | 2.33 | 2.33 |
| 365.44 | 2.33 | 2.33 |
| 353.40 | 2.46 | 2.46 |
| 337.39 | 1.11 | 1.11 |
| 353.38 | 1.55 | 1.55 |