Basic Information
ID: ALA4180102
Type: Functional
Description: Positive allosteric modulation of rat M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium mobilization
Organism: Rattus norvegicus
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4180102
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 341.44 | 3.43 | 3.43 |
| 299.36 | 3.26 | 3.26 |
| 311.79 | 2.74 | 2.74 |
| 338.39 | 3.52 | 3.52 |
| 444.46 | 3.11 | 3.11 |
| 373.46 | 3.14 | 3.14 |
| 367.40 | 3.75 | 3.75 |
| 400.40 | 3.88 | 3.88 |
| 401.30 | 4.17 | 4.17 |
| 366.85 | 3.52 | 3.52 |
| 351.38 | 2.40 | 2.40 |
| 396.88 | 3.53 | 3.53 |
| 398.41 | 3.47 | 3.47 |
| 360.41 | 2.97 | 2.97 |
| 368.39 | 3.14 | 3.14 |
| 254.33 | 3.09 | 3.09 |
| 384.84 | 3.66 | 3.66 |
| 412.44 | 3.78 | 3.78 |
| 401.30 | 4.17 | 4.17 |
| 366.85 | 3.52 | 3.52 |
| 400.40 | 3.88 | 3.88 |
| 398.41 | 3.47 | 3.47 |
| 384.84 | 3.66 | 3.66 |
| 401.30 | 4.17 | 4.17 |
| 391.48 | 3.05 | 3.05 |
| 401.39 | 3.28 | 3.28 |
| 338.38 | 3.93 | 3.93 |
| 366.85 | 3.52 | 3.52 |
| 401.39 | 3.28 | 3.28 |
| 400.40 | 3.88 | 3.88 |