Assay Report Card

Basic Information

ID: ALA4180103

Type: Functional

Description: Positive allosteric modulation of rat M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium mobilization relative to acetylcholine

Organism: Rattus norvegicus

Cell type: CHO

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
373.463.143.14
367.403.753.75
400.403.883.88
401.304.174.17
366.853.523.52
351.382.402.40
396.883.533.53
398.413.473.47
368.393.143.14
254.333.093.09
384.843.663.66
412.443.783.78
401.304.174.17
366.853.523.52
400.403.883.88
398.413.473.47
384.843.663.66
401.304.174.17
391.483.053.05
401.393.283.28
338.383.933.93
366.853.523.52
401.393.283.28
400.403.883.88