Basic Information
ID: ALA4180466
Type: ADME
Description: Antagonist activity at human 5-HT3A receptor expressed in HEK293 cells assessed as inhibition of 5-HT-induced calcium flux preincubated for 30 mins prior to 5-HT addition by Fluo-4 AM dye based FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4180466
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 269.35 | 2.20 | 2.20 |
| 323.32 | 2.91 | 2.91 |
| 363.05 | 2.26 | 2.26 |
| 289.77 | 2.55 | 2.55 |
| 289.77 | 2.55 | 2.55 |
| 269.35 | 2.20 | 2.20 |
| 363.05 | 2.26 | 2.26 |
| 269.35 | 2.20 | 2.20 |
| 285.35 | 1.90 | 1.90 |
| 361.45 | 3.57 | 3.57 |
| 255.32 | 1.89 | 1.89 |
| 323.32 | 2.91 | 2.91 |
| 255.32 | 1.89 | 1.89 |
| 323.32 | 2.91 | 2.91 |
| 363.05 | 2.26 | 2.26 |
| 289.77 | 2.55 | 2.55 |
| 289.77 | 2.55 | 2.55 |