Basic Information
ID: ALA4181290
Type: Binding
Description: Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured after 1 min
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4181290
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 452.85 | 6.55 | 6.55 |
| 518.90 | 7.08 | 7.08 |
| 523.29 | 6.25 | 6.25 |
| 485.35 | 6.72 | 6.72 |
| 554.33 | 7.13 | 7.13 |
| 446.34 | 4.86 | 4.86 |
| 467.36 | 6.58 | 6.58 |
| 446.34 | 5.84 | 5.84 |
| 501.90 | 6.40 | 6.40 |
| 509.38 | 6.63 | 6.63 |
| 472.38 | 6.37 | 6.37 |
| 484.32 | 6.13 | 6.13 |
| 498.37 | 5.98 | 5.98 |
| 488.42 | 6.03 | 6.03 |
| 520.30 | 7.33 | 7.33 |
| 445.35 | 5.47 | 5.47 |
| 535.35 | 7.60 | 7.60 |
| 486.33 | 6.11 | 6.11 |
| 473.40 | 6.25 | 6.25 |
| 457.36 | 6.73 | 6.73 |
| 468.89 | 6.20 | 6.20 |
| 533.05 | 8.11 | 8.11 |
| 519.31 | 7.94 | 7.94 |
| 483.33 | 6.74 | 6.74 |
| 458.35 | 6.13 | 6.13 |
| 554.33 | 7.13 | 7.13 |
| 519.31 | 7.94 | 7.94 |
| 496.40 | 6.59 | 6.59 |
| 469.30 | 7.06 | 7.06 |
| 533.05 | 8.11 | 8.11 |
| 473.28 | 5.62 | 5.62 |
| 454.93 | 6.46 | 6.46 |
| 536.34 | 6.99 | 6.99 |
| 474.39 | 5.78 | 5.78 |
| 536.34 | 6.99 | 6.99 |