Basic Information
ID: ALA4181673
Type: Functional
Description: Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced cAMP accumulation preincubated for 10 mins followed by forskolin stimulation measured after 10 to 60 mins by ELISA based chemiluminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4181673
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 607.68 | 5.08 | 5.08 |
| 518.56 | 5.62 | 5.62 |
| 541.62 | 5.28 | 5.28 |
| 516.57 | 5.43 | 5.43 |
| 530.57 | 5.87 | 5.87 |
| 512.58 | 5.73 | 5.73 |
| 559.61 | 5.42 | 5.42 |
| 527.55 | 4.74 | 4.74 |
| 462.45 | 4.39 | 4.39 |
| 511.55 | 5.29 | 5.29 |
| 516.57 | 5.43 | 5.43 |
| 504.53 | 5.56 | 5.56 |
| 516.57 | 5.43 | 5.43 |
| 558.54 | 5.29 | 5.29 |
| 600.58 | 5.59 | 5.59 |
| 572.57 | 5.85 | 5.85 |
| 410.45 | 3.96 | 3.96 |
| 557.55 | 5.90 | 5.90 |
| 566.59 | 5.44 | 5.44 |