Basic Information
ID: ALA4181680
Type: Binding
Description: Inhibition of Plasmodium falciparum DHFR using DHF as substrate preincubated for 15 mins followed DHF addition measured after 15 mins by spectrophotometric method
Organism: Plasmodium falciparum
Activity Charts
Bioactivity
Activity Types for Assay ALA4181680
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 248.72 | 2.52 | 2.52 |
| 357.41 | -1.46 | -1.46 |
| 434.52 | 3.61 | 3.61 |
| 476.97 | 4.04 | 4.04 |
| 426.52 | 3.31 | 3.31 |
| 413.49 | 2.77 | 2.77 |
| 430.49 | 3.52 | 3.52 |
| 430.49 | 3.52 | 3.52 |
| 456.51 | 3.11 | 3.11 |
| 464.93 | 4.17 | 4.17 |
| 418.53 | 3.44 | 3.44 |
| 472.55 | 3.40 | 3.40 |
| 472.55 | 3.40 | 3.40 |
| 470.53 | 3.15 | 3.15 |
| 440.55 | 3.70 | 3.70 |
| 474.65 | 4.92 | 4.92 |
| 418.55 | 3.65 | 3.65 |
| 462.56 | 4.53 | 4.53 |
| 480.49 | 4.40 | 4.40 |
| 457.49 | 3.29 | 3.29 |
| 442.52 | 3.39 | 3.39 |
| 402.46 | 2.97 | 2.97 |
| 442.52 | 3.39 | 3.39 |
| 430.49 | 3.52 | 3.52 |