Basic Information
ID: ALA4181722
Type: Binding
Description: Inhibition of recombinant Cav1.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by KCl addition by Fluo-4-AM dye-based FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Voltage-gated L-type calcium channel alpha-1C subunit(ALA1940)
Document: ALA4177680
Inhibition of recombinant Cav1.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by KCl addition by Fluo-4-AM dye-based FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4181722
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.43 | 4.02 | 4.02 |
| 370.40 | 3.46 | 3.46 |
| 443.43 | 3.88 | 3.88 |
| 429.40 | 3.63 | 3.63 |
| 325.80 | 3.77 | 3.77 |
| 415.38 | 3.59 | 3.59 |
| 425.41 | 3.97 | 3.97 |
| 373.46 | 3.68 | 3.68 |