Basic Information
ID: ALA4181741
Type: ADME
Description: Apparent permeability across basolateral to apical side in MDCK cells expressing MDR1 at 1 uM measured every 30 mins for 2 hrs
Format: BAO_0000219
Organism: Canis lupus familiaris
Cell type: MDCK
Target: ADMET(ALA612558)
Document: ALA4177680
Apparent permeability across basolateral to apical side in MDCK cells expressing MDR1 at 1 uM measured every 30 mins for 2 hrs: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4181741
Papp
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 424.45 | 3.64 | 3.64 |
| 443.43 | 4.02 | 4.02 |
| 406.40 | 3.15 | 3.15 |
| 446.43 | 4.09 | 4.09 |
| 398.37 | 2.84 | 2.84 |
| 429.40 | 3.63 | 3.63 |
| 415.42 | 3.33 | 3.33 |
| 415.38 | 3.59 | 3.59 |
| 425.41 | 3.97 | 3.97 |
| 433.41 | 3.38 | 3.38 |