ID: ALA4181949
Type: ADME
Description: Inhibition of human CYP1A2 expressed in yeast microsomal membranes using 3-cyano-7-ethoxycoumarin as substrate measured after 10 mins by fluorescence assay
Organism: Homo sapiens
Subcellular Fraction: Microsomal Membrane
Bioactivity
Activity Types for Assay ALA4181949
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
272.30 | 4.61 | 4.61 |
259.31 | 4.13 | 4.13 |
239.27 | 2.99 | 2.99 |
299.33 | 3.00 | 3.00 |
269.30 | 2.99 | 2.99 |
313.35 | 3.39 | 3.39 |
239.27 | 2.99 | 2.99 |
327.38 | 3.78 | 3.78 |
253.26 | 2.71 | 2.71 |
341.41 | 4.17 | 4.17 |
239.27 | 2.99 | 2.99 |
313.35 | 3.39 | 3.39 |
269.30 | 2.99 | 2.99 |
299.33 | 3.00 | 3.00 |