Basic Information
ID: ALA4181950
Type: ADME
Description: Inhibition of human CYP2D6 expressed in yeast microsomal membranes using 7-ethoxy-methyloxy-3-cyanocoumarin as substrate measured after 10 mins by fluorescence assay
Organism: Homo sapiens
Subcellular Fraction: Microsomal Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA4181950
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.30 | 4.61 | 4.61 |
| 259.31 | 4.13 | 4.13 |
| 239.27 | 2.99 | 2.99 |
| 299.33 | 3.00 | 3.00 |
| 269.30 | 2.99 | 2.99 |
| 313.35 | 3.39 | 3.39 |
| 239.27 | 2.99 | 2.99 |
| 327.38 | 3.78 | 3.78 |
| 253.26 | 2.71 | 2.71 |
| 341.41 | 4.17 | 4.17 |
| 239.27 | 2.99 | 2.99 |
| 313.35 | 3.39 | 3.39 |
| 269.30 | 2.99 | 2.99 |
| 299.33 | 3.00 | 3.00 |