Basic Information
ID: ALA4181961
Type: ADME
Description: Inhibition of recombinant human CYP2C19 expressed in HEK293 cells using 3-cyano-7-ethoxycoumarin as substrate pretreated for 30 mins followed by substrate addition measured for 60 mins by fluorescence assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4181961
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.30 | 4.61 | 4.61 |
| 259.31 | 4.13 | 4.13 |
| 239.27 | 2.99 | 2.99 |
| 299.33 | 3.00 | 3.00 |
| 269.30 | 2.99 | 2.99 |
| 313.35 | 3.39 | 3.39 |
| 239.27 | 2.99 | 2.99 |
| 327.38 | 3.78 | 3.78 |
| 253.26 | 2.71 | 2.71 |
| 341.41 | 4.17 | 4.17 |
| 239.27 | 2.99 | 2.99 |
| 313.35 | 3.39 | 3.39 |
| 269.30 | 2.99 | 2.99 |
| 299.33 | 3.00 | 3.00 |