Basic Information
ID: ALA4182025
Type: Functional
Description: Positive allosteric modulation of human wild type M1 receptor assessed as increase in acetylcholine-induced calcium flux by FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4182025
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 286.79 | 4.15 | 4.15 |
| 300.81 | 3.95 | 3.95 |
| 298.44 | 4.00 | 4.00 |
| 342.90 | 5.49 | 5.49 |
| 346.86 | 5.09 | 5.09 |
| 314.84 | 4.71 | 4.71 |
| 328.87 | 4.95 | 4.95 |
| 342.90 | 5.49 | 5.49 |
| 312.80 | 4.15 | 4.15 |
| 308.45 | 4.61 | 4.61 |
| 335.90 | 4.35 | 4.35 |
| 286.79 | 4.60 | 4.60 |
| 259.76 | 4.30 | 4.30 |
| 311.82 | 4.20 | 4.20 |
| 324.45 | 4.31 | 4.31 |
| 344.87 | 5.03 | 5.03 |
| 380.88 | 5.81 | 5.81 |
| 270.33 | 3.42 | 3.42 |
| 380.88 | 5.81 | 5.81 |
| 331.24 | 4.04 | 4.04 |
| 326.85 | 5.22 | 5.22 |
| 378.42 | 5.20 | 5.20 |
| 344.87 | 4.33 | 4.33 |
| 361.83 | 4.60 | 4.60 |
| 308.41 | 3.87 | 3.87 |
| 303.79 | 5.05 | 5.05 |
| 266.37 | 3.67 | 3.67 |
| 340.88 | 5.10 | 5.10 |
| 294.85 | 4.71 | 4.71 |
| 342.90 | 5.35 | 5.35 |
| 344.84 | 4.85 | 4.85 |
| 266.37 | 3.59 | 3.59 |
| 330.84 | 4.29 | 4.29 |
| 329.86 | 4.35 | 4.35 |
| 297.34 | 3.19 | 3.19 |
| 344.87 | 4.07 | 4.07 |
| 316.86 | 5.26 | 5.26 |
| 363.31 | 5.61 | 5.61 |
| 362.42 | 5.32 | 5.32 |
| 342.90 | 5.61 | 5.61 |
| 346.86 | 5.09 | 5.09 |
| 291.38 | 3.54 | 3.54 |
| 344.87 | 4.47 | 4.47 |
| 334.92 | 5.49 | 5.49 |
| 342.90 | 4.98 | 4.98 |
| 396.23 | 4.02 | 4.02 |
| 396.87 | 5.97 | 5.97 |
| 352.85 | 4.33 | 4.33 |
| 328.87 | 5.10 | 5.10 |
| 368.81 | 5.25 | 5.25 |
| 252.34 | 3.28 | 3.28 |
| 312.74 | 3.41 | 3.41 |
| 325.84 | 4.47 | 4.47 |
| 329.86 | 4.35 | 4.35 |
| 328.87 | 4.95 | 4.95 |
| 300.81 | 4.32 | 4.32 |
| 289.79 | 4.20 | 4.20 |
| 358.85 | 3.86 | 3.86 |
| 370.52 | 5.97 | 5.97 |
| 295.41 | 3.64 | 3.64 |
| 328.87 | 4.95 | 4.95 |
| 320.34 | 4.30 | 4.30 |
| 377.34 | 6.00 | 6.00 |
| 304.78 | 4.07 | 4.07 |