Assay Report Card

Basic Information

ID: ALA4182103

Type: Functional

Description: In vivo agonist activity at NPR-A in Crl:CD(SD) rat assessed as increase in cGMP accumulation in plasma at 1 mg/kg/min, iv administered via infusion for 15 mins measured after 30 mins by radioimmunoassay

Organism: Rattus norvegicus

Strain: Crl:CD(SD)

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
539.663.663.66
524.644.024.02
538.674.274.27
523.664.694.69