Basic Information
ID: ALA4182208
Type: Binding
Description: Inhibition of HCV genotype 1a H77 NS3 protease infected in human HuH7 replicon cells assessed as reduction in viral replication after 4 days by luciferase reporter gene assay
Organism: Hepatitis C virus (isolate H77)
Activity Charts
Bioactivity
Activity Types for Assay ALA4182208
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 748.30 | 3.85 | 3.85 |
| 828.31 | 4.76 | 4.76 |
| 752.93 | 4.22 | 4.22 |
| 780.98 | 4.85 | 4.85 |
| 738.90 | 3.83 | 3.83 |
| 826.03 | 3.82 | 3.82 |
| 824.01 | 3.57 | 3.57 |
| 724.88 | 3.44 | 3.44 |
| 795.01 | 5.08 | 5.08 |
| 766.96 | 4.44 | 4.44 |
| 841.98 | 3.18 | 3.18 |
| 766.96 | 4.61 | 4.61 |
| 724.88 | 3.66 | 3.66 |
| 726.89 | 3.90 | 3.90 |
| 794.89 | 4.67 | 4.67 |
| 795.01 | 5.08 | 5.08 |
| 780.98 | 4.85 | 4.85 |
| 780.98 | 5.00 | 5.00 |
| 738.90 | 3.88 | 3.88 |
| 797.97 | 3.04 | 3.04 |
| 740.92 | 4.12 | 4.12 |